Thomas Eye Group

Early Keratoconus Signs You Should Never Ignore

By Dr. David Sackel

David J Sackel MD Cornea Specialist & Comprehensive Ophthalmologist

Have you noticed changes in your vision? Maybe you’ve recently had an eye exam and purchased a new pair of glasses within the last year, but words and objects are starting to look blurry or distorted again. If you’re experiencing frequent changes in your vision, it might be due to keratoconus, which is an eye disease that affects the cornea.

Keratoconus causes the clear, front part of the eye to progressively thin and bulge. If left untreated, keratoconus can lead to significant vision loss. The good news is that early detection can help preserve your sight. Thomas Eye Group’s experienced corneal specialist uses advanced imaging technology to diagnose, monitor, and treat keratoconus.

What is Keratoconus and Why Does It Develop?

Keratoconus is a progressive eye condition that’s characterized by the gradual thinning of the cornea. As the cornea thins, it starts to bulge outward, making it resemble a cone. As the cornea becomes increasingly cone-shaped, it changes the way the light enters your eye, leading to blurriness and distortions, glare around lights, and problems seeing and driving at night.

What Happens to the Cornea in Someone Who Has Keratoconus?

Keratoconus Comparison Diagram

In people without keratoconus, the cornea remains smooth and rounded, like a small dome. This allows light to enter the person’s eye and focus correctly on the retina. In people with keratoconus, the cornea gets progressively weaker and thinner. As the cornea thins, it starts to bulge outward, changing the way light enters the eye.

Is Keratoconus Genetic or Environmental?

The exact causes of keratoconus are not known. However, in the United States, it’s believed that approximately 55 out of 100,000 people have the condition, according to the American Academy of Ophthalmology. Additionally, research suggests that nearly 1 in 10 people who have keratoconus have a parent with the condition. Keratoconus usually becomes noticeable in the teenage years or early 20s, and consequently, that’s typically when it’s diagnosed.

Environmental factors that may contribute to the development of the condition include allergies and excessive eye rubbing. It’s also believed that having a connective tissue disorder, especially Marfan syndrome or Ehlers-Danlos syndrome, is associated with an increased risk.

How Does Collagen Play a Role in Corneal Strength?

Cornea structure diagram.

The cornea has several layers, including the epithelium, Bowman’s layer, stroma, Descemet’s membrane, and endothelium. Of those layers, the stroma is the thickest, and it’s mainly composed of type I collagen, which is the most common collagen type. In fact, it’s estimated that about 90 percent of all the collagen in the human body is type I.

Normally, the collagen in the stroma is neatly organized, like a mesh net or scaffold, where every fiber is organized and linked. In an eye that has keratoconus, the interlinked collagen scaffolding becomes weak and disorganized. Once this happens, the cornea starts to slowly bulge.

First Signs of Keratoconus to Watch For?

Keratoconus is a slowly progressive eye disease. People don’t often realize they have it until their glasses suddenly stop correcting their vision or their contacts no longer fit comfortably.

Keratoconus symptoms include:

  • Sudden blurriness
  • Ghosting around objects and people
  • Seeing halos or glare around lights, especially at night
  • Increasing sensitivity to light
  • Frequent changes to your glasses or contact lens prescription

Why Do Glasses Suddenly Stop Correcting Your Vision?

Keratoconus causes a pronounced bulge in the cornea that affects the way light enters the eye. It’s important to note that keratoconus often occurs in both eyes, but one eye may be worse than the other. Because of the way keratoconus distorts the shape of the eye, it can be increasingly difficult to correct refractive errors with glasses and standard contact lenses.

How Is Keratoconus Different from Regular Astigmatism?

Cases of astigmatism are diagnosed when the cornea is misshapen. Instead of being round, like a basketball or dome, it’s more oval-shaped, like a football. Astigmatism also doesn’t cause corneal weakness. With keratoconus, the cornea weakens, bulges, and eventually resembles a cone.

Dangers of Untreated Keratoconus

It’s important to understand that keratoconus is a progressive eye disease. This means that the condition often starts out mild, and glasses and standard contact lenses usually correct the refractive errors. However, as the disease progresses, it can be harder to correct the person’s vision. The good news is that early treatment can help preserve vision for longer.

Can Keratoconus Lead to Blindness?

Keratoconus doesn’t often lead to complete blindness. However, it has the potential to result in severe vision impairment. Without treatment, even specialty contact lenses, like scleral lenses, may not be able to restore clear vision.

When Does a Thinning Cornea Become Severe?

The cornea can become too thin for treatment, which is when keratoconus is often designated as severe. At this stage, the cornea is often severely scarred, and the affected person usually has significant visual impairment. Ophthalmologists often recommend corneal transplants to help restore vision.

Modern Keratoconus Treatments that Stop or Slow Down Keratoconus

There are several treatments that can help treat, slow, or stop the progression of keratoconus, including scleral contact lenses and keratoconus surgery, which includes a corneal cross-linking procedure and corneal transplants.

Scleral Contact Lenses

Scleral contacts are rigid gas-permeable lenses that are designed to go completely over the cornea with the edges resting on the white part of the eye (sclera). They are often prescribed to keratoconus patients because they can help dramatically improve vision by correcting irregular astigmatism.

Corneal Cross-Linking Surgery (CXL)

Corneal cross-linking surgery was approved by the FDA in 2016 as a keratoconus treatment. It helps strengthen the collagen fibers in the cornea in people with keratoconus and post-LASIK ectasia. This minimally invasive procedure uses a special form of ultraviolet (UV) light and vitamin B2 (riboflavin) eye drops to strengthen the cornea’s natural collagen fibers. This creates new “cross-links” that make the cornea stiffer and more stable, preventing further bulging or thinning. It’s important to understand that cross-linking doesn’t reverse the damage already caused by keratoconus, but it is effective at slowing and even stopping the progression. The procedure takes about 60 minutes. Patients are sent home with a temporary contact lens and a bandage over their eye. The lens and bandage are to remain in place for about a week. Once the bandage comes off and the lens is removed, it can take a few weeks to a few months for the vision in the eye to clear. Most people experience a temporary haziness or blurriness that resolves over time.

Corneal Transplants

In rare, advanced cases of keratoconus, where the cornea becomes severely scarred or thin, a cornea transplant, sometimes called a keratoplasty, may be recommended. During this procedure, the damaged corneal tissue is replaced with healthy donor tissue. This helps to restore clear vision. Corneal transplants are highly successful. In fact, the rejection rate is only about 10 percent.

What Should You Do if You Suspect Keratoconus?

If you have a family history of keratoconus or have noticed changes in your vision, you should schedule an eye appointment with Dr. David Sackel, our board-certified, fellowship-trained cornea specialist. Several procedures can be used to diagnose changes in the cornea, including an eye refraction, which helps determine your eyeglasses or contact lens prescription, a slit-lamp examination, which is used to view the surface of the eye and look at the shape of the cornea, keratometry, which helps determine the basic shape of the cornea, and corneal mapping, which is used to create a map of the shape of the cornea. These eye tests can help diagnose keratoconus in the early stages so that it can be monitored and treated.

Conclusion

If you’re experiencing symptoms of keratoconus, like halos, glare or frequent changes in your glasses or contact lens prescription, you may have keratoconus. The good news is that early detection and keratoconus treatment can help slow or stop the progression. To schedule an appointment for a corneal evaluation at one of our Atlanta Eye Care Centers, contact us today.

About David J. Sackel, MD

David J. Sackel, M.D. is a board-certified ophthalmologist specializing in cornea and external disease, cataract surgery, and refractive surgery. He graduated magna cum laude from Duke University, earned his M.D. from the University of Pennsylvania School of Medicine and an MBA from the Wharton School, then completed his ophthalmology residency at New York University and a cornea fellowship at Emory University.